Representative turbidimetric clotting profiles. (A) Clotting profiles of purified fibrin (3 mg/mL) with increasing concentrations of rM1 (0-60 μg/mL) (n = 4). Maximum absorbance parameters extracted from the turbidity clotting profiles in (B) plasma and (C) purified conditions (n = 4). (D) Clotting time was analyzed using a thrombin time assay with a micro-mechanical clot detection KC4 coagulometer in varying concentrations of rM1 (0-60 μg/mL). The dotted lines represent the baseline (absence of M1) condition (n = 4). Error bars represent standard error of the mean (∗P < .05, ∗∗P < .01, ∗∗∗P < .001, ∗∗∗∗P < .0001, 1-way analysis of variance [ANOVA] with Dunnett post hoc test).
Figure 1.

Representative turbidimetric clotting profiles. (A) Clotting profiles of purified fibrin (3 mg/mL) with increasing concentrations of rM1 (0-60 μg/mL) (n = 4). Maximum absorbance parameters extracted from the turbidity clotting profiles in (B) plasma and (C) purified conditions (n = 4). (D) Clotting time was analyzed using a thrombin time assay with a micro-mechanical clot detection KC4 coagulometer in varying concentrations of rM1 (0-60 μg/mL). The dotted lines represent the baseline (absence of M1) condition (n = 4). Error bars represent standard error of the mean (∗P < .05, ∗∗P < .01, ∗∗∗P < .001, ∗∗∗∗P < .0001, 1-way analysis of variance [ANOVA] with Dunnett post hoc test).

This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal