M1 protein impacts fibrin film formation. (A) LSCM of plasma fibrin film with and without the presence of rM1. Fibrin fibers were formed through the addition of thrombin in the presence or absence of 1.88 μg/mL rM1. Scale bar: 20 μm. n = 1. (B) LSCM of plasma fibrin film with increasing concentrations of rM1 (0-60 μg/mL). n = 3. Fibrinogen was fluorescently labelled with Alexa Fluor 594. Images were constructed in Imaris software. Scale bar: 20 μm. Fibrin film (arrow) forms a continuous layer on the surface of the clot, distinct from the fibrin fibers underneath.
Figure 6.

M1 protein impacts fibrin film formation. (A) LSCM of plasma fibrin film with and without the presence of rM1. Fibrin fibers were formed through the addition of thrombin in the presence or absence of 1.88 μg/mL rM1. Scale bar: 20 μm. n = 1. (B) LSCM of plasma fibrin film with increasing concentrations of rM1 (0-60 μg/mL). n = 3. Fibrinogen was fluorescently labelled with Alexa Fluor 594. Images were constructed in Imaris software. Scale bar: 20 μm. Fibrin film (arrow) forms a continuous layer on the surface of the clot, distinct from the fibrin fibers underneath.

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