Spatial mapping of genes associated with translocations detected by diagnostic FISH. (A) H&E images of PCs of representative samples overlaid with XBP1 transcripts (green) to identify PCs and expression of genes commonly upregulated in association with the displayed cytogenetic alteration (scale bar, 10 μm). (B) Samples are grouped by cytogenetic category as determined by diagnostic FISH testing. The size and color intensity of each dot represent the relative expression of selected genes commonly upregulated in association with the specific cytogenetic alteration. H&E, hematoxylin and eosin.