Dietary Trp alters the risk of venous thrombogenicity in a syngeneic colon cancer model. Age-matched C57BL/6 female mice were used as in Figure 1. (A) Averages of tumor growth in all 3 dietary groups are shown. Error bars represent standard deviation. (B) Representative harvested tumors from the 3 groups are shown. (C) Averages of tumor weights in the 3 experimental groups are shown (zero Trp vs 0.2% Trp [normal] vs 1.2% Trp [high]). Error bars represent SEM. (D) Representative images of H&E-stained tumor tissue sections are shown at 40× and 100× original magnifications (scale bars, 25 μm [40×] and 50 μm [100×]). (E) Averages of normalized clot weights in female mice under 6 experimental conditions. Two-factor ANOVA showed P value <.001. Error bars represent SEM. (F) Averages of normalized clot weights in male mice under 6 experimental conditions. The number of mice analyzed under each condition is denoted by dots in each bar graph. Error bars represent SEM. Two-factor ANOVA test showed P value <.001. ns, nonsignificant. ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.0001, ^###P < 0.0001, ^####P < 0.0001.