Clonal architecture and molecular composition of distinct RASp mutant genes in CMML. Each row corresponds to a given RASp gene as labeled on the graph. For each gene, the relative frequency of associated comutated genes is indicated by the bar plots. Bar plots in green (top 6) and orange (middle 6) represent the frequencies of clones for a given gene appearing as codominant or subclonal events to each specific RASp mutation, respectively. Bar plots in red (bottom 6) represent the frequency of dominant clones for each gene in cases in which each specific RASp mutation appeared as subclonal events.
Figure 3.

Clonal architecture and molecular composition of distinct RASp mutant genes in CMML. Each row corresponds to a given RASp gene as labeled on the graph. For each gene, the relative frequency of associated comutated genes is indicated by the bar plots. Bar plots in green (top 6) and orange (middle 6) represent the frequencies of clones for a given gene appearing as codominant or subclonal events to each specific RASp mutation, respectively. Bar plots in red (bottom 6) represent the frequency of dominant clones for each gene in cases in which each specific RASp mutation appeared as subclonal events.

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