SOMs of unsupervised analysis of the clinical and biological characteristics of 61 patients with SCD and acute parvovirus B19 infection. Unsupervised analysis of the clinical and biological characteristics of the 61 patients with SCD and parvovirus B19 infection. Patients with similar characteristics are located by the SOM algorithm closely on the maps, within one of the small groupings (“districts”). Each individual map shows the mean values or proportions per district for each characteristic: blue indicates the lowest average values, red the highest, with numbers shown for a selection of representative districts in each SOM. For instance, patients with erythroblastopenia were more frequently located in the lower left districts and had SS genotype, lower baseline hemoglobin, higher platelet counts, and less requirement for vasopressors and mechanical ventilation. 1, cluster 1; 2, cluster 2; 3, cluster 3; ACP, acute cor pulmonale; ARDS, acute respiratory distress syndrome; FiO2, fraction of inspired O2; Hb, hemoglobin; HR, heart rate; IMV, invasive mechanical ventilation; LOS, length of stay; RR, respiratory rate; SpO2, oxygen peripheral saturation.