MND-c.o.RAG1 LV correction (+LV) rescues in vitro T-cell development of HSPCs from RAG1-SCID patients (p1-p3). (A) Flow cytometry of week 8 ATOs. CD7+CD5+ and subsequent T-cell plots are gated on live CD45+CD14–CD19–CD56– cells. (B) Absolute cell number per ATO (week 8) of live CD45+ and subpopulations, as indicated.

MND-c.o.RAG1 LV correction (+LV) rescues in vitro T-cell development of HSPCs from RAG1-SCID patients (p1-p3). (A) Flow cytometry of week 8 ATOs. CD7+CD5+ and subsequent T-cell plots are gated on live CD45+CD14CD19CD56 cells. (B) Absolute cell number per ATO (week 8) of live CD45+ and subpopulations, as indicated.

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