Pirtobrutinib efficacy in patients with R/R FL. Best change in sum of product diameters from baseline. Data for 4 patients are not shown in the waterfall plot due to no measurable target lesions identified by computed tomography scan at baseline, discontinuation before first response assessment, or lack of adequate imaging in follow-up. Data cutoff of 27 January 2025. ∗Indicates patient with a >100% increase in sum of products of diameter, with the corresponding change from baseline of 145.1.