Change in pain NRS scores in adults and adolescents in the primary efficacy set after exa-cel infusion. (A) Mean adult pain NRS score by study visit. (B) Mean adolescent pain NRS score by study visit. Dotted lines indicate the measure for mild pain (3 points). Baseline is defined as the most recent nonmissing measurement (scheduled or unscheduled) collected before the start of mobilization. BL, baseline; M, month; SE, standard error.