Variation in weight gain of Townes mice. (A) Mice transduced with 1 × 10¹⁴ vg/kg rAAV8-mHPX vector (n = 15) compared with mice treated with the control vector (n = 10); (B) mice transduced with 2 × 10¹³ vg/kg rAAV8-hHPX vector (n = 5) compared with mice treated with the control vector (n = 3). The results are expressed as weight gain (g) per basal weight. The results are presented as mean ± SEM, and P values are from the Mann-Whitney U test.