Liver histology. (A) Representative images of H&E stained liver sections from Townes mice treated with rAAV8-hHPX or control (rAAV8-Empty) vectors. No evidence of inflammation, fibrosis, or necrosis were observed. Original magnification ×400. (B) Results from individual mice; n = 3 to 6 per group. Analysis performed by 2 blinded observers. Single-cell necrosis denotes sparse and rare events. H&E, hematoxylin and eosin; M, mouse.