Pooled 12-week TI rates in patients with TD LR-MDSs treated with luspatercept. This forest plot presents the pooled 12-week TI rates from studies evaluating Lusp in patients with TD LR-MDSs. Each blue square indicates the point estimate for an individual study, with the horizontal lines representing 95% CIs. Square sizes are proportional to the study weights in the meta-analysis. The diamond at the bottom represents the overall estimate derived using a random-effects model. Lusp, luspatercept.