Effect of obexelimab on the in vitro production of anti-RBC autoantibodies in stimulated cultures. Delta percentage of anti-RBC autoantibodies production with obexelimab (red), rituximab (light red), and control IgG isotype (blue) in 48-hour PHA-stimulated (A) and 7-day PWM-stimulated cultures (B). Delta percentage was calculated for each cytokine in the presence of obexelimab (15 μg/mL) over cultures performed in the absence of the drug.