Flow diagram for comparative analyses cohorts. Flow diagram depicting the 3 different cohorts included in the comparative analyses. Of 121 patients with TA-TMA from the KSCTG registry, 111 had ≥2 risk factors for death/poor outcome and, therefore, were the comparison group vs patients from the OMS721-TMA-001 study. All 121 KSCTG patients with TA-TMA had ≥1 high-risk factor and were compared with patients in the EAP cohort.