Figure 1
A.Cutaneous GvHD scoring. Mice transplanted with TH17 cells were treated with either 16mg/kg of control IgG or anti-IL-22 antibody once a week for four weeks. Mice were scored twice a week using an established scoring system: 0: No ulcers or alopecia; 1: Skin ulcers with alopecia less than 1cm2 in area; 2: 1-2 cm2 in area; 3: Greater than 2cm2 in area; an additional score of 0.3 is added if mice have ulcers or scaling on paws, tail, or ears. B. Acute GvHD scoring. Mice were scored twice a week using an established scoring system.
