Impaired neutrophil response in oxazolone-induced acute dermatitis in mindin-deficient mice. (A) Neutrophil responses in the ear dermis of oxazolone-treated mice. Oxazolone was applied to the ears of wild-type and mindin^-/- mice (n = 3). Six hours later, neutrophil migration to the affected area was examined in tissue sections. Shown are mean ± SD of neutrophils. Data are representative of 2 independent experiments. ^*P < .001. (B) Immunofluorescence staining of ear dermis of wild-type and mindin^-/- mice. Tissue sections were stained with polyclonal antimindin antibody followed by FITC-anti–rabbit immunoglobulin G (IgG). Tissue structure under light microscopy with a 10 ×/0.30 objective lens is also shown (original magnification, × 100).