Correlation between changes in NT-proBNP levels and hematologic response to chemotherapy in 51 AL patients with cardiac involvement. (A) Twenty patients in whom NT-proBNP decreased by 30% or more, or normalized; median NT-proBNP modification –52% (range: –95% to –30%). (B) Thirty-one patients in whom NT-proBNP was stable or increased, median NT-proBNP modification +37% (range: –24% to +1862%). The difference between A and B was statistically significant (P < .001) by the Mann-Whitney U test.