Coagulation parameters in WT, FG^–/–, L^–/–, and L^–/–/A^–/–/FG^–/– mice. (A) PT, (B) aPTT, (C) plasma levels of fibrinogen, and (D) plasma levels of TAT. N = the number of mice used at each time point. ▪ indicates WT; ▦, FG^–/–; □, L^–/–/A^–/–; and ▤, L^–/–/A^–/–/FG^–/–. *P < .01.