Figure 4.
Eosinophil infiltration in the liver, kidney, and lung of murine eosinophilic disease model induced by F/P fusion gene and IL-5 overexpression. Histopathologic analysis of liver (A), kidney (B), and lung (C) in IL-5Tg-F/P recipient mice was performed by hematoxylin and eosin (A-C) and anti-MBP staining (C [inset]). Representative examples (of 3-7 mice per group, pooled from three independent experiments) are shown. Optical magnifications × 125. Insets represent blow-ups of original pictures with overall magnifications of × 2000 in panels A-B and × 500 in C. Arrow is pointing to an eosinophil infiltrate in the (A) liver and (B) kidney.