Figure 5.
Quantitative histopathologic analysis of the heart and small intestine in the murine eosinophilic disease model induced by F/P fusion gene and IL-5 overexpression. Representative examples (of 3-4 mice per group) of eosinophil content of heart (A) and small intestine (B) of non–Tg-mock, non–Tg-F/P, IL-5Tg-mock, and IL-5Tg-F/P mice are shown in panels A-B. Optical magnifications × 125. Quantitative analysis of the content of MBP+ eosinophils in heart (C) and small intestine (D) of mice depicted in panels A-B was performed. Data are shown as mean ± SD. *P < .05 and **P < .01, compared with non–Tg-mock; #P < .05 and ##P < .01, compared with IL-5Tg-mock.