Response rates to second-line therapy. (A) Response rates evaluated at 30 days of second-line treatment for acute GvHD in all 61 eligible patients. CR indicates complete responses; PR, partial responses; stable, stable disease; and worse, patients with progressive GvHD. (B) Responses in 61 patients according to randomization arm: no ATG (gray bars) or ATG (black bars). There is no significant difference in responses (48% vs 55% CR + PR; P = .3) in the 2 treatment groups, or in patients who worsened or died (15% vs 26%, P = .2).