Figure 2.
Immune resistance to MAPC in Rag2–/– mice. (A) With the use of WBI of firefly luciferase bioluminescence, the biodistribution of donor MAPC DLs was monitored in real time. In T- and B-cell–deficient Rag2–/– mice (n = 5), MAPC DLs were detected throughout the 30-day period and even more so (B) in the mice given the anti–NK1.1 monoclonal antibody (n = 5). MAPC DL–derived BLI signals were observed predominantly over the area of upper thorax.