Fever responses of the chimeric mice. Abdominal temperature (mean ± SE) responses of the 4 indicated types of chimeric mice to LPS (50 μg/kg, intravenously) or saline (1 mL/kg, intravenously) are shown. At the time of the injection, the values of abdominal temperature of LPS- and saline-treated mice were, respectively, 35.7 ± 0.2°C (n = 7) and 35.9 ± 0.2°C (n = 6) for the HeOuJ mice with HeOuJ bone marrow, 36.0 ± 0.2°C (n = 7) and 36.2 ± 0.4°C (n = 7) for the HeJ mice with HeJ bone marrow, 35.9 ± 0.2°C (n = 9) and 35.9 ± 0.2°C (n = 7) for the HeOuJ mice with HeJ bone marrow, and 36.2 ± 0.3°C (n = 7) and 35.9 ± 0.2°C (n = 5) for the HeJ mice with HeOuJ bone marrow. These values did not differ statistically from each other.