Figure 4.
The GFTP of patient G does not localize to the Golgi. Fibroblasts derived from LAD II patient G were transiently transfected with GFP-tagged GFTPs from a healthy donor, the Turkish LAD II patient, 3 Arab LAD II patients, and patient G, respectively. Cells were double-stained with anti-GFP antibodies and antibodies against the Golgi protein golgin-97. One representative experiment of 3 is shown. Bar represents 10 μm.