CD44 mediates phagocytosis of large particles. (A) Schematic representation of the construction of an erythrocyte-biotin-avidin-biotinylated-antibody (Ebab) beginning with the erythrocyte “E” through to the mature prey Ebab. (B) Efficiency of phagocytosis of CD44 and IgG_2b-coated Ebabs as well as IgG- and iC3b-opsonized erythrocytes by RAW macrophages. Phagocytosis was recorded as the phagocytic index; mean ± SE of 4 separate experiments.