PI3 kinase is involved in CD44-mediated phagocytosis. (A-B) Confocal fluorescent and transmitted light images of RAW cells transfected with Akt-PH-GFP and presented with CD44 Ebabs. The solid line represents 5 μm. (C-D) Efficiency of phagocytosis of CD44 Ebabs by RAW cells preincubated with increasing doses of LY-294002 or wortmannin. *Different from 0 μM LY-294002; P < .05, mean ± SE of 4 separate experiments. **Different from 0 μM wortmannin; P < .05, mean ± SE of 4 separate experiments.