Figure 8.
Figure 8. CD44-mediated phagocytosis results in formation of a mature phagosome. (A-B) Confocal fluorescent and transmitted light images, respectively, of LysoTracker Red DND-99 staining during the late stages of CD44-mediated phagocytosis (30 minutes), indicating phagosome-lysosome fusion. The solid line represents 10 μm. (C) Phagocytosis of CD44 Ebabs stimulates production of reactive oxygen species by murine neutrophils. *Different from nonimmune IgG2b-Ebab; P < .05, mean ± SE of 3 separate experiments.

CD44-mediated phagocytosis results in formation of a mature phagosome. (A-B) Confocal fluorescent and transmitted light images, respectively, of LysoTracker Red DND-99 staining during the late stages of CD44-mediated phagocytosis (30 minutes), indicating phagosome-lysosome fusion. The solid line represents 10 μm. (C) Phagocytosis of CD44 Ebabs stimulates production of reactive oxygen species by murine neutrophils. *Different from nonimmune IgG2b-Ebab; P < .05, mean ± SE of 3 separate experiments.

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