Figure 3.
![Figure 3. IRp60 inhibits eosinophil-mediated fibroblast proliferation. Eosinophils previously incubated with either anti-IRp60 or control antibodies (isotype, anti-p58.2) followed by the cross-linker sheep anti-mouse F(ab′)2 were washed and incubated with various concentrations of IL-5/GM-CSF (50 ng/mL) for 18 to 20 hours. Cell supernatants were assessed for their ability to induce 3T3 fibroblast proliferation as assessed by [3H]-thymidine incorporation. Data are expressed as mean CPM/well ± SD (n = 3; **P < .005).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/107/5/10.1182_blood-2005-07-2926/2/zh80050691790003.jpeg?Expires=1735843422&Signature=M7CdFLUv5uEIfcMkDZRp5b63fdOxvJ3bm8UuzEYrXE-FXhX0qNd1054juA1xL52Y1MOg0Jasykjv1aueR5CI9Oof5ob859jv79ySKnbFU0j0okA3zeAjj0n7jJPu5~bPUawzkiwo~SVBF3oQVvSN80aOmSZ6e9TSYLE05yNRbvCOyTCfFDfkYOr-O2iLScVVMul7eRtQGeKnyXfK3Y4nTOK7J3mt~y1I9Tivyymc90T96OFYKbs7FhuEJ5P9dzMY9zufYEHUQ4flKuLsZOvdb-quN1aMH2pXZNuBKTe81Bhb0jecSD5GbiCkB5oHtQwd84ZmU39gndzwGd7lKxGTGg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
IRp60 inhibits eosinophil-mediated fibroblast proliferation. Eosinophils previously incubated with either anti-IRp60 or control antibodies (isotype, anti-p58.2) followed by the cross-linker sheep anti-mouse F(ab′)2 were washed and incubated with various concentrations of IL-5/GM-CSF (50 ng/mL) for 18 to 20 hours. Cell supernatants were assessed for their ability to induce 3T3 fibroblast proliferation as assessed by [3H]-thymidine incorporation. Data are expressed as mean CPM/well ± SD (n = 3; **P < .005).
