Figure 6.
ATRA/FK228 induces G0/G1 cell-cycle arrest in NB4 cells. (A) Example of flow cytometric cell-cycle analysis with PI stain of NB4 cells treated with ATRA (1 μM) and/or FK228 (3.0 nM) for 72 hours, as described in “Flow cytometric analysis.” (B) Graphs show the mean ± SD of data of G1-phase cell population (i) and S-phase cell population (ii) from 3 independent experiments. A statistically significant difference was determined by ANOVA and Fisher post hoc tests (*P < .05; **P < .01).
