Survivin expression and cell viability in KBM5 and KBM5-STI571 cells treated with Sur-AS-ODN. (A) Sur-AS-ODN induced a dose- and time-dependent down-regulation of survivin protein and (B) down-regulation of survivin expression resulted in decreases in the viability of both KBM5 and KBM5-STI571 cells. Sol cont indicates solution T control; prog cont, nucleofection program K17 control; NS, Sur-NS-ODN control; AS, Sur-AS-ODN.