The effect of sequentially removing subjects with iron deficiency, the α-thalassemia -3.7-kb allele, sickle trait, serum creatinine levels of more than 1.4 mg/dL, and those who had filled prescriptions for ACE inhibitors on the hemoglobin level (Hb) of African-American men and women and of age- and sex-matched white controls. An expansion of Figure 2 from Beutler and West.2 The effect on the hemoglobin level (Hb) of African-American men and women and of age- and sex-matched white controls of sequentially removing subjects with the following characteristics: iron deficiency, the α-thalassemia 3.7-kb allele, sickle trait, serum creatinine levels higher than 123.76 μM (1.4 mg/dL), and having filled a prescription for an ACE inhibitor. Top graph, women; bottom graph, men. Fe def indicates iron deficiency; Thal, α-thalassemia 3.7-kb allele; S, sickle trait; Creat, serum creatinine levels higher than 1.4 mg/dL; and ACE-I, a history of having filled a prescription for an ACE inhibitor. Error bars indicate SEM.
