Role of DNAM-1 in the recognition of mDCs by normal NK cells in an allogeneic setting. Activated polyclonal NK cells from donor no. 10 (A) and the representative NK cell clone no. 19-7 (B), selected as “alloreactive” against donor no. 2 (see “Materials and methods”), were analyzed for their cytolytic activity against mDCs derived from this donor. Effector cells were preincubated with medium alone (control) or with mAbs to the indicated molecules, used alone or in combination. The E/T ratio used was 10:1. The results are representative of 3 independent experiments; the SD of the mean of the triplicates was less than 5%.