Overall survival of 151 AML patients, by study, FLT3/ITD mutation status, and ITD size. Kaplan-Meier estimates are shown. Tick marks indicate censored observations. (A) Study SWOG-9333 (patients aged 56-84 years). (B) Study SWOG-9500 (patients aged 18-55 years). The effect of ITD size on overall survival did not differ significantly between the 2 studies (P = .17).