γδ T-cell-deficient recipients do not have increased incidence or severity of GVHD. Combined data from 3 experiments. On day 0, BALB/c (H-2^d) recipient mice were lethally irradiated and reconstituted with 8 × 10⁶ T-cell-depleted B10.D2 (H-2^d) bone marrow (BM) cells alone (n = 28, both recipient types) or BM plus 10⁷ B10.D2 spleen cells (spl): wild-type (WT) recipients (n = 41) or TCRδ^-/- recipients (n = 38). (A) Incidence of clinical skin GVHD. (B) Clinical skin score. Average clinical score for mice affected with GVHD (unaffected mice are excluded). BM control mice did not get GVHD and are represented on the graph as scoring 0. (C) Weight loss. (D) Pathologic skin disease. Representative mice were killed for pathologic analysis, and histologic cutaneous GVHD was scored by a dermatopathologist blinded to experimental groups.