Intracellular IFN-γ expression. (A) Intracellular IFN-γ expression in CD3⁺ or CD4⁺ cells stimulated with PHAin the presence of different concentrations of bortezomib (1 of 5 similar experiments is shown). (B) Box plot of CD4⁺IFN⁺ cells for the different doses of bortezomib for the 5 samples analyzed. Error bars indicate 95% confidence intervals.