Tumorigenesis in VavP-MYC mice.MYC10 (n = 53), MYC10^hom (n = 29), MYC12 (n = 19), MYC17 (n = 23; data from Smith et al25), and wild-type (B6) (n = 25) mice were monitored for tumors and killed when sick. The percentage of mice surviving at weekly intervals is shown. Log-rank analysis comparing wild-type versus MYC12, MYC12 versus MYC10, MYC10 versus MYC10^hom, and MYC10^hom versus MYC17 showed that in all cases survival was significantly different (P < .001).