IL-7Rα and IL-15Rα expression on EBV-specific CD8⁺ T cells. Representative staining profiles are shown for CD8⁺ T cells specific for (A) the HLA-B^*0801-restricted EBV lytic cycle epitope RAK and (B) for the HLA-B^*0801-restricted EBV latent cycle epitope, FLR. (Left panels) Flow cytometry profiles of tetramer versus CD8 staining among PBMCs; percentage values refer to the percentage of tetramer-positive cells in the CD8⁺ population. (Middle and right panels) Flow cytometry profiles of tetramer versus IL-7Rα and tetramer versus IL-15Rα staining among CD8⁺ T cells, respectively; percentage values refer to the percentage of IL-Rα-positive cells within the tetramer-positive population. From top to bottom, panels show the profiles obtained from one HLA-B^*0801-positive patient, IM141, studied in acute phase (IM141.1), 3 months later (IM141.2), and 2 years later (IM141.5), all stained in the same experiment alongside cells from an HLA-B^*0801-positive healthy EBV carrier with no history of IM.