Figure 2.
Relation between results of the simplified flow cytometric assays with those of more complex MRD assays. Bone marrow samples collected on day 19 of remission induction therapy from children with B-lineage ALL were examined for the presence of CD19+ cells coexpressing CD10 and/or CD34. Results were compared with those obtained with several sets of 4-antibody combinations in 376 patients (A), and with those of PCR amplification of immunoglobulin and T-cell receptor genes in 149 patients (B). Results of Spearman rank correlations are shown.