Figure 4.
Hox and TALE gene expression in leukemia specimens. Expression of Hox and TALE genes in BM cells from leukemic mice as evaluated by absolute quantitative RT-PCR. Mice are grouped according to the inducing oncogene listed on the top. Morphologic classification group and expression levels of Mac-1 and c-Kit are provided for each mouse. CT values were normalized for 18S expression levels determined in 25 ng total RNA (CT = 9). CT values from all genes were then converted into copy numbers (cn) based on the formula cn = 2(38–ct). Visualization of expression levels was enhanced by color gradient based on a logarithmic scale of cn values.