Figure 3.
Effect of endothelial VCAM-1 deficiency on MCp recruitment to the inflamed lung. (A) Number of lung MNCs recovered per mouse from OVA-sensitized C57BL/6 (▪) and VCAM-1-deficient (□) mice with and without aerosolized OVA challenges. Values are the mean ± SEM from 3 separate experiments with MNCs pooled from 2 to 3 mice in each experiment. (B) Concentration of MCp's (MCp's/106 MNCs) in the lungs of the same mice. (C) Total number of MCp's per lung in the same mice. *Indicates statistical significance (P < .05) as determined by the 1-tailed Student t test.