Figure 5.
Platelet recovery after immune-induced thrombocytopenia is similar in αIIb+/- and αIIb-/- mice. Whole-blood platelet counts from αIIb+/- (♦, dashed line) or αIIb-/- (▪, solid line) mice were obtained prior to immune-induced thrombocytopenia (time point 0, n = 6), followed by injection of 2 μg/g anti-GPIbα antibody. Whole-blood platelet counts were then collected at the indicated time points after injection. Error bars represent SEM; n = 2 for 3-, 48-, and 72-hour time points, n = 4 for 120-hour time point.