Deregulated chemokine expression in p100^−/− spleens. Total RNA from wild-type and p100^−/− spleens was analyzed for chemokine expression by QRT-PCR. Relative mRNA expression corrected for β-actin levels is shown. Error bars indicate SD from 3 to 4 experiments. Significant differences are indicated (Student t test, **P < .01; ***P < .002).