Rapid response and mortality in the 4 treatment arms of LCH-I and LCH-II. The achievement of a rapid response (left panel) and the 5-year mortality (right panel) of RO⁺ patients in the individual treatment arms of LCH-I (A and B) and LCH-II (A and B) displayed according to increasing treatment intensity (left to right) are compared. Error bars represent SEM.