Figure 5
Figure 5. Concentrations of IFN-γ and IL-6 in cocultures with mIg- or TT-pulsed autologous DCs. Supernatants from cocultures with mIg-, TT- and unpulsed DCs, as well as from anti-CD3–stimulated PBMCs, were collected for analysis of cytokine concentrations by cytometric bead array. IFN-γ (left graph) and IL-6 (right graph) were measured in such cultures for 8 of the patients with a proliferative response towards mIg-pulsed DCs (Figure 2) and 5 of the 6 patients that had received a TT vaccination (Figure 4). The mean concentrations (+SD) are shown (y-axis in log scale).

Concentrations of IFN-γ and IL-6 in cocultures with mIg- or TT-pulsed autologous DCs. Supernatants from cocultures with mIg-, TT- and unpulsed DCs, as well as from anti-CD3–stimulated PBMCs, were collected for analysis of cytokine concentrations by cytometric bead array. IFN-γ (left graph) and IL-6 (right graph) were measured in such cultures for 8 of the patients with a proliferative response towards mIg-pulsed DCs (Figure 2) and 5 of the 6 patients that had received a TT vaccination (Figure 4). The mean concentrations (+SD) are shown (y-axis in log scale).

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