Figure 6
![Figure 6. Stimulation of TLR3 on host hematopoietic APCs enhances GVT response. BMT and tumor induction were performed in [WT-B6→B6Ly5.2] and [Tlr3−/−B6→B6Ly5.2] animals as described in “Materials and methods.” The recipient animals received TLR3 stimulant polyI:C or the diluent control and were analyzed for GVHD and tumor-free survival. (A) Tumor mortality data for [WT-B6→B6Ly5.2] and [Tlr3−/−B6→B6Ly5.2] animals with 2 × 104 MBL-2 cells (n = 5 to 14 per group, pooled from 2 experiments). (B) Representative photos from bioluminescence study at day 21 after allo-BMT.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/121/20/10.1182_blood-2012-05-432872/2/4231f6.jpeg?Expires=1735822666&Signature=BCIgPTyskD7H4CCSruIg5XMr5RH1semZJEcTxAr9qFdGPd1rl~LxLpowYbfBGh6QpUAOgD3j2Jr3fgJGZiN8HJx0ssSKMfjWkE74~G7c-2nvQhvB0w526sWtXDp9nexN-VHgjSY2EsBYosdRMymGeuRuO58fGi9h4mImCsqwMh8Qii9L1QUusSqdZOPcDmHDl0PZdXx6UIJ4G7rmGQRufeCBbiQrjrBAFjoyNzRueABfqkNRDkcxkJLSeze390TJmmPvVoSs5Rde6QVlA0PUpBLr6rLbL9BoX9fdQlUWcAGbj3uK1MrGgIwZnKVAA1M4ck4WVR0iDom1pnYPwEX64g__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Stimulation of TLR3 on host hematopoietic APCs enhances GVT response. BMT and tumor induction were performed in [WT-B6→B6Ly5.2] and [Tlr3−/−B6→B6Ly5.2] animals as described in “Materials and methods.” The recipient animals received TLR3 stimulant polyI:C or the diluent control and were analyzed for GVHD and tumor-free survival. (A) Tumor mortality data for [WT-B6→B6Ly5.2] and [Tlr3−/−B6→B6Ly5.2] animals with 2 × 104 MBL-2 cells (n = 5 to 14 per group, pooled from 2 experiments). (B) Representative photos from bioluminescence study at day 21 after allo-BMT.
