MYC/BCL2 coexpression contributes to the inferior prognosis of ABC-DLBCL. (A-B) OS (A) and PFS (B) of the ABC vs GCB subtype of DLBCL in the entire training set. COO classification of 411 cases was based on GEP results and 55 cases based on IHC results. (C-D) OS (C) and PFS (D) of the ABC vs GCB subtype of DLBCL after all MYC⁺BCL2⁺ cases were excluded. (E-F) OS (E) and PFS (F) of the ABC vs GCB subtype in MYC⁺BCL2⁺ DLBCL.