DFS by IKZF1 deletion variant in EsPhALL good-risk patients. DFS curves of EsPhALL good-risk patients by IKZF1 wild-type and deletion variants (A), with 2- and 4-year estimates (SE) (B). CR1, first complete remission; dominant negative, samples with exons 4-7 deletions involving at least 1 allele; haploinsufficient, samples with total deletions plus exons 2-7 deletions, plus samples with exon 2 involving 1 allele; miscellaneous, samples not classified in previous groups.