Low doses of RG7112 and Peg IFNα reduce PV and PMF CFU-GM– and BFU-E–derived colony formation. (A) Effects of 200 nM of RG7112 combined with 200 ng/mL of Peg-IFNα 2a on CFU-GM– and BFU-E–derived colony formation by normal BM CD34⁺ cells (n = 5). (B) Effects of 200 nM of RG7112 combined with 200 ng/mL of Peg-IFNα 2a on CFU-GM– and BFU-E–derived colony formation by PV CD34⁺ cells (n = 22). (C) Effects of 200 nM of RG7112 combined with 200 ng/mL of Peg-IFNα 2a on CFU-GM– and BFU-E–derived colony formation by PMF CD34⁺ cells (n = 7).