Western blot results show that low doses of RG7112 and Peg-IFNα 2a increase p21 and PUMA protein levels in PV CD34⁺ cells. (A) Western blotting shows p21 and PUMA protein levels in 2 individual PV samples after treatment with low doses of RG7112 or Peg-IFNα 2a alone or in combination. (B) The ratio of the degree of p21/GAPDH in PV samples. (C) Western blotting of p21 and PUMA protein levels in 2 individual normal samples after treatment with low doses of RG7112 or Peg-IFNα 2a alone or in combination. (D) The ratio of the degree of p21/GAPDH in normal samples.