Reconstituting ILCs are activated and express markers associated with tissue homing. (A) Expression of the early activation marker CD69 (upper panels) and the proliferation antigen Ki-67 (lower panels) after induction chemotherapy (before HSCT, white bars) and 12 weeks after allogeneic HSCT (gray bars). (B) Expression of molecules associated with homing to gut (α4β7 and CCR6) or skin (CCR10 and CLA) was mutually exclusive. A representative example of homing marker expression on Lin⁻ CD127⁺ ILC is depicted. (C) Expression of α4β7 (upper panels) and CCR6 (lower panels) after induction chemotherapy (before HSCT, white bars) and 12 weeks after allogeneic HSCT (gray bars). (D) Expression of CCR10 (upper panels) and CLA (lower panels) after induction chemotherapy (before HSCT, white bars) and 12 weeks after allogeneic HSCT (gray bars). Data are shown as median values with interquartile ranges. *P < .05, **P < .01, ***P < .001. HC, healthy controls (black bars, n = 8). Patient data are taken from cohort 2, Table 1 (n = 40). ND, not determined.